I'm about 8 hours into it, and I dig it so far. It's utterly unique. Really, there's no other game like it.
It's pretty interesting to see a guy as ambitious as Kojima have a vision to make something completely out there, and then there being one publisher who's willing to write him a blank check and then get out of the way. Doesn't happen much any more.
I like the gameplay. It has a tactile feel to it that keeps things engaging and it's incredibly satisfying when you finish a long delivery. The stealth and fighting elements are usually simple but they add variety and don't feel frustrating.
The social building system is a cool idea and it works surprisingly well.
The game's world feels well-realized and the story is somewhere between fine and good.
All that said, it's absolutely gonna be hated by plenty of people. The pace is slow as hell, the gameplay is definitely not for everyone, it's got the usual Kojima excesses, and Jesus Christ the Monster Energy product placement is annoying.
Oh, and apparently Guillermo del Toro doesn't voice his own character. I know English isn't his first language, but he's perfectly fluent as far as I know.