I used to love Retronauts, now it just grates on me. This is thanks to the ultra annoying Bob Mackey and the amount of advertisements they have now. Plus they've been podcasting for so long they are constantly going over old topics. But honestly this is a problem with most retro podcasts. The Shane/Koehler days are that show's sweet spot.
I've been digging RGDS as it's neat to hear gaming experiences from the other side of the pond. But it's not as good since Andy left.
Hardcore Gaming 101's show is pretty great too.